(annual causes of death by cause)

Tobacco - 435,000
Poor Diet and Physical Inactivity - 365,000
Alcohol- 85,000
Microbial Agents- 75,000
Toxic Agents- 55,000
Motor Vehicle Crashes - 26,347
Adverse Reactions to Prescription Drugs - 32,000
Suicide- 30,622
Incidents Involving Firearms - 29,000
Homicide - 20,308
Sexual Behaviors - 20,000
All Illicit Drug Use, Direct and Indirect - 17,000
Non-Steroidal Anti-Inflammatory Drugs Such As Aspirin - 7,600
Marijuana - 0